Molecular Rods with Oligospiroketal Backbone as Anchors in Biological Membranes
P. Müller, J. Nikolaus, S. Schiller, A. Herrmann, K. Möllnitz, S. Czapla, P. Wessig – 2009
Getting stuck in: A hydrophobic molecular rod with terminal fluorescent moieties has been synthesized. The insertion of the rod into membranes was investigated and shown to incorporate efficiently into model and biological membranes (see picture; gray C, blue N, red O). Those rods can be used as stable membrane-associated anchors for functionalization of membrane surfaces.