Controlled Assembly of Vesicle-based Nanocontainers on Layer-by-Layer Particles via DNA Hybridization
M. Loew, J. Kang, L. Dähne, R. Hendus-Altenburger, O. Kaczmarek, J. Liebscher, D. Huster, K. Ludwig, C. Böttcher, A. Herrmann, A. Arbuzova – 2009
Microscopic colloidal particles allow a precise regulation of chemical reactions in time and place. A controlled assembly of multiple layers of intact lipid vesicles on a solid support provided by layer-by-layer particles functionalized by a covalent attachment of DNA oligonucleotides is reported (see image). Lipophilic complementary oligonucleotides are incorporated into lipid vesicles. Fusion of liposomes and release can be triggered.