Synthesis of Heterocycles via Alkoxyallenes.

T. Lechel, H.-U. Reissig – 2010

Lithiated alkoxyallenes are very versatile components for the synthesis of heterocycles such as furans, pyrroles, and 1,2-oxazines, easily allowing the preparation of natural products via these heterocyclic intermediates. A surprising three-component synthesis of N‑acylated enaminones allowed the synthesis of highly functionalized 4-hydroxypyridines, 5‑acetyloxazoles, and pyrimidines. All these heterocyclic products are ready for further functionalizations, in particular for palladium-catalyzed reactions, leading to libraries of new interesting heterocycles.

Titel
Synthesis of Heterocycles via Alkoxyallenes.
Verfasser
T. Lechel, H.-U. Reissig
Datum
2010
Kennung
10.1002/chem.2001100382
Quelle/n
Zitierweise
Pure Appl. Chem. 2010, 82, 1835-1844.
Art
Text
dfg_logo